Skip to main content

Featured boutique hotel destinations

Destination inspiration for your trip – find a boutique hotel

The 10 Best Florida Keys Boutique Hotels – Design Hotels in Florida Keys, United States

Check out our pick of great boutique hotels in Florida Keys

Filter by:


Review score

Superb: 9+ Very good: 8+ Good: 7+ Pleasant: 6+
Our top picks Lowest price first Star rating and price Top reviewed

See the latest prices and deals by choosing your dates.

Douglas House 3 stars

Duval, Key West

Located just 2 minutes’ walk from the Ernest Hemingway Home and Museum, this adult-only inn features free parking and a shared outdoor swimming pool. Free Wi-Fi is also available.

A microwave, refrigerator and coffee-making facilities come standard in each room at Douglas House. Guests rooms also include a cable TV. Amenities, location, clean. Very good location in Keywest, I strongly endorse this location

Show more Show less
9
Superb
2,460 reviews
Price from
£285
per night

Simonton Court Historic Inn & Cottages 4 stars

Duval, Key West

Located in Key West, this Florida adult-only inn offers complimentary, light continental breakfast and free Wi-Fi access. Duval Street is 2 minutes’ drive from the property and The Ernest Hemingway Home and Museum is 3 minutes’ drive away. Staffs really kindly...the place clean, breakfast very good and mainly the attention with our aniversary! Amazing place and location is perfect.

Show more Show less
9.2
Superb
1,090 reviews
Price from
£382
per night

Truman Hotel 3 stars

Duval, Key West

This trendy Key West boutique hotel features an outdoor pool and modern rooms equipped with iPod docking stations and flat-screen TVs. South Beach - Key West is 0.5 miles away from the property.

All rooms at the Truman Hotel are equipped with a refrigerator. Each room is styled with wood floors, and bathrooms boast tiled showers and marble vanities. Some rooms offer a private patio. The hotel is very beautiful with a very nice and clean pool area. Rooms were moden, clean and comfortable. The included breakfast and happy hour were simple but more than enough and very good. Staff were very friendly and the location was perfect. Everything was great. Very good value for money in the Key West.

Show more Show less
9
Superb
2,683 reviews
Price from
£382
per night

Old Town Manor 3 stars

Duval, Key West

This adult-only, pet friendly, smoke-free property is located in the heart of Key West less than 1.6 km from the Southernmost Point. Guests will enjoy a daily breakfast including pastries, organic fruit, and dessert cakes during their stay. So convenient, perfect location right behind Deval St….. love the old charm of the house. Quite, nice landscaping excellent breakfast!! We will definitely be returning

Show more Show less
9
Superb
953 reviews
Price from
£236
per night

Key West Villas

Duval, Key West

Located in the heart of historic Key West, guests will be 1 minutes’ walk from Duval Street. A heated pool, daily continental breakfast, and free WiFi are provided.

All rooms feature a private bath, small refrigerator, and microwave. Apartments at Key West Villas include a fully-equipped kitchen and seating area. The couple who run the villas are charming. They greeted us with cocktails and made us feel comfortable at all times. The place is beautiful and the location is fantastic, just off the main street in Key West.

Show more Show less
9.7
Exceptional
335 reviews
Price from
£293
per night

The Artist House 3 stars

Duval, Key West

This historical Key West bed and breakfast is 1 mile from the Southernmost Point and 3 minute’s walk from iconic Duval Street. The Artist House guests will enjoy a daily continental breakfast and spa hot tub. The service of the staff is outstanding. They made us feel special and at home from the first minute. The house has a very interesting history and famous thrilling story but you need to hear it first hand. The rooms are large and very comfortable. All well airconditioned. The location is excellent and close to the main attractions. The breakfast are excellent with a wide selection. The selection of coffee is also excellent. Happy hour at 4pm is brilliant and the hosts are very generous with wine, beer , cake and other snacks. The splash pool was a life saver. The one day was 100+F and we spent 3 hours in the pool cooling down. It was such a social occasion with other guests.

Show more Show less
9.1
Superb
139 reviews
Price from
£422
per night

Andrews Inn & Garden Cottages

Duval, Key West

Located right off Duval Street, the Andrews Inn and Garden Cottages are less than 5 minutes’ walk from various dining and entertainment options. Guests can enjoy free WiFi and an outdoor pool.

A flat-screen TV and an iPod docking station are featured in each classic room at this Key West bed and breakfast. Guests will also enjoy the convenience of a refrigerator in their room. Rooms also have a clock radio with auxiliary cables. The inn is beautiful, perfectly located, excellent amenities and benefits (breakfast, happy hours, pool), the room was cute and nothing was missing, and Isabella is the nicest person you could meet in Key West. Thank you!

Show more Show less
9.3
Superb
103 reviews
Price from
£328
per night

The Gardens Hotel 4 stars

Duval, Key West

Located in Key West, Florida, this adult-only hotel offers two outdoor pools. Duval Street is a 1-minute walk away, and Key West Butterfly and Nature Conservatory is 3 minutes’ drive from the hotel.

A private balcony or patio with property views is provided in all rooms at The Gardens Hotel Key West. A flat-screen cable TV, ironing facilities, and a refrigerator are also featured in each room. Loved the location and the staff, perfect vacation. Thanks so much.

Show more Show less
9.6
Exceptional
142 reviews
Price from
£358
per night

The Grand Guesthouse 3 stars

Downtown Key West, Key West

This all-adult bed and breakfast is within a 10-minute walk of Duval Street and the Atlantic Ocean. This environmentally-friendly inn offers in-room refrigerators, bicycle rentals and a continental breakfast. Lovely owner, neat and tidy housing, quiet location, rich breakfast, free parking lots in front of the hotel, late check-in no problem

Show more Show less
9.2
Superb
664 reviews
Price from
£250
per night

Coconut Palm Inn 3 stars

Tavernier, Key Largo

Overlooking the Florida Bay, this inn is nestled in a coconut grove, directly on the beach in Key Largo and offers private boat docks and wireless internet access throughout the property.

Guests at the Coconut Palm Inn will enjoy easy access to sport fishing, diving and snorkelling. After a day of kayaking, guests can relax beside the outdoor swimming pool or cook a meal on the barbecue grills. What a spectacular hideaway - so cosy, relaxed and situated in a beautiful landscape. We enjoyed every single moment with a perfect start of the day serving coffee and muffins for free. The pool just in front of our room never was crowded, most of the time we had it for our own... Lots of water sports equipment as kayaks, SUP's and others were available and at night all guests joined the fire place for Marshmallows... very nice idea...

Show more Show less
9.1
Superb
182 reviews
Price from
£338
per night

Most booked boutique hotels in Florida Keys this month

Boutique Hotels that guests love in Florida Keys